We draw from the genius
of nature and respect
nature in return.
aXichem is based on research and product development, and strives constantly to develop and improve the product.
At present, the Company is specifically working with the development of alternative capsaicin isomers, mainly ethyl and butyl capsaicin. The company has also focused on continuous improvement of industrial process synthesis to achieve an optimal starting point for large-scale production. The work of new isomers as well as the industrial process synthesis is carried out by chemists with long experience from both experimental chemistry and industrial chemistry. A number of analyzes and studies are currently underway.
In addition, aXichem, in collaboration with established actors in marine antifouling and chicken food, has worked on the development of end products. These experimental products have been tested and developed under conditions that are as close to commercial use as possible under product development. The completed tests have yielded very good results, and aXichem's ongoing collaborations on product development continue.
Latest Scientific Reports
February 21, 2024
aXivite: Connecting the Gut with Weight Management and Muscle Health
The amount of research on gut health has grown significantly in the past decade. The connection between the gut and other health conditions is often called the Gut___-Axis. The "blank" includes areas such as metabolic, brain, joint, skin, immune, muscle health and many more. The new and cutting-edge nutraceutical ingredient aXivite has shown in clinical studies to impact three specific areas of gut, metabolic and muscle health. When we look at these three, we can see that they may even form a health triangle where each may be connected.
January 31, 2024
“Effects of Different Phenylcapsaicin Doses on Neuromuscular Activity and Mechanical Performance in Trained Male Subjects”
Journal: Frontiers in Physiology DOI: 10.3389/fphys.2023.1215644
This study aimed to examine the effects of Phenylcapsaicin on neuromuscular activity and mechanical performance in trained male subjects. It investigated the influence of low and high doses of Phenylcapsaicin compared to a placebo, focusing on aspects like full squat performance, muscle activity, perceived exertion, muscle damage, protein breakdown, metabolic response, and recovery.
Pablo Jiménez-Martínez, Juan Sánchez-Valdepeñas, Pedro J Cornejo-Daza, Clara Cano-Castillo, Iván Asín-Izquierdo, Carlos Alix-Fages, Fernando Pareja-Blanco, Juan C Colado
January 31, 2024
“Effects of Phenylcapsaicin on Aerobic Capacity and Physiological Parameters in Active Young Males”
Journal: Frontiers in Physiology DOI: 10.3389/fphys.2023.1190345
This study assessed the impact of Phenylcapsaicin on aerobic capacity, energy metabolism, and exercise physiological variables in young males. The findings suggested an improvement in fat oxidation and maximum heart rate, contributing to increased aerobic capacity.
Pablo Jiménez-Martínez, Carlos Alix-Fages, Danica Janicijevic, Sergio Miras-Moreno, Sara Chacón-Ventura, Juan J Martín-Olmedo, Juan Carlos De La Cruz-Márquez, Francisco J Osuna-Prieto, Lucas Jurado-Fasoli, Francisco J Amaro-Gahete, Amador García-Ramos, Juan C Colado
January 31, 2024
“Effects of Different Phenylcapsaicin Doses on Resistance Training Performance, Muscle Damage, Protein Breakdown, Metabolic Response, Ratings of Perceived Exertion, and Recovery”
Journal: Journal of the International Society of Sports Nutrition DOI: 10.1080/15502783.2023.2204083
This research explored the effects of different doses of Phenylcapsaicin on resistance training performance and recovery in males. The high dose of Phenylcapsaicin showed improvements in squat performance and reduced muscle damage, highlighting its potential as an ergogenic aid.
Pablo Jiménez-Martínez, Pedro Jesús Cornejo-Daza, Juan Sánchez-Valdepeñas, Iván Asín-Izquierdo, Clara Cano-Castillo, Carlos Alix-Fages, Fernando Pareja-Blanco, Juan C Colado
January 12, 2024
“Effects of phenylcapsaicin supplementation on physical performance and mechanical, metabolic, biochemical, perceptual and electrophysiological fatigue” International Doctoral Thesis presented by: D. Pablo Jiménez Martínez
Doctoral Program in Physical Activity and Sport
Department of Physical Education
Faculty of Physical Education
Valencia, October 2023
D. Pablo Jiménez Martínez
June 21, 2021
aXivite, a safe and effective treatment for healthy weight loss and improved body shape while simultaneously mitigating the effects of GI inflammation
October 01, 2018
Article in ”Toxicology Research and Application” – a 90-day toxicity and genotoxicity study with high-purity phenylcapsaicin
Published in:
Toxicology Research and Application
Published 2018
Torbjørn Rage Paulsen, Sebastian Stiller, Klaus Weber, Claudia Donath, Gudrun Schreiband, and Knut Helge Jensen
September 26, 2018
Article published in “Toxicology Research and Application”
Toxicology Research and Application has published article about Axiphen.
September 26, 2018
aXichem ser mycket positiva resultat av aXiphen® som salmonellahämmare hos kycklingar i kommersiell produktionsanläggning
Published 2018
September 06, 2018
aXichem har slutfört tester som visar att aXiphen® hämmar salmonella hos svin
September 02, 2018
aXiphen®feed i fodret ökar tillväxten med i genomsnitt nioprocent samt minskar salmonella hos kycklingar
September 02, 2018
Activation of TRPV1 by Dietary Capsaicin Improves Endothelium-Dependent Vasorelaxation and Prevents Hypertension
September 02, 2018
Capsaicin and capsiate could be appropriate agents for treatment of obesity:
September 02, 2018
Capsaicin in Metabolic Syndrome
September 02, 2018
Gut Microbiota Mediates the Protective Effects of Dietary Capsaicin against Chronic Low-Grade Inflammation and
September 02, 2018
Non-Pungent Capsaicin Analogs (Capsinoids) Increase Metabolic Rate and Enhance Thermogenesis via Gastrointestinal TRPV1 in mice
September 02, 2018
Cough reduction using capsaicin.
September 02, 2018
Role of Capsaicin in Cancer Prevention
Company description
We draw from the genius
of nature and respect
nature in return.
aXichem has built a strong global patent portfolio with molecule patents of phenylcapsaicin and derivatives, manufacturing method for phenylcapsaicin and derivatives, and various application patents within our focus areas. See below selected examples.
aXichem has also submitted two new patent applications:
1) Phenylcapsaicin and derivatives as bioenhancer for selected substrates
2) Phenylcapsaicin as physical performance aid.
NO345530B1
Synthesis of capsaicin derivatives
Patent Granted
BR112018007151B1 / EP3358965B1
Bird feed and in particular poultry feed
comprising synthetic capsaicinoid derivatives and such feed for prophylactic use or treatment of salmonella infection.
